非布索坦2020年价格

Febuxostat (febuxostat, feburic) is a xanthine oxidase (XO) inhibitor and is suitable for the long-term treatment of hyperuricemia with gout symptoms. Febuxostat has the strongest uric acid-lowering effect and has relatively fewer side effects.

Febuxostat (febuxostat, feburic) is a drug approved in 2009 for the treatment of chronic hyperuricemia, with the trade name Uloric. In 2013, febuxostat was launched in China. Compared with the traditional treatment drug allopurinol, febuxostat (febuxostat, feburic) is more effective in reducing uric acid. The most common adverse reactions are abnormal liver function, diarrhea and rash. The medication guide recommends a starting dose of 40 mg/d. In patients with mild to moderate renal impairment (creatinine clearance [CrCl] 30-89 mL/min), the starting dose is the same as in patients with normal renal function.

Febuxostat price in 2020: Febuxostat produced by Zydus Pharmaceuticals in India has the same efficacy as the original drug, but the price is indeed much lower. The specification is 80mg*30 tablets/box. Its price is about 80$, and the specification is 40mg*100 tablets/box and the price is about 200$.

The recommended initial dose of febuxostat (febuxostat, feburic) is 40 mg once a day (some foreign instructions recommend a starting dose of 20 mg, once a day). After taking the drug for 2 to 5 weeks, recheck the blood uric acid. Gradually increase the dosage according to the blood uric acid value, with each increment of 20 mg. The maximum daily dose is 80 mg. After the blood uric acid value reaches the target, maintain the lowest effective dose. Food and antacids have no effect on taking this medicine.

In the early stages of treatment, the rapid decrease in blood uric acid levels may cause more urate deposited in tissues to be mobilized, leading to an increase in the frequency of gout attacks. In order to prevent gout attacks in the early stages of treatment, it is recommended to start with a small dose and gradually increase the dose, and use colchicine and non-steroidal anti-inflammatory drugs (such as ibuprofen, etc.) under the guidance of a doctor.