非布索坦哪里有卖的?
Febuxostat (febuxostat, feburic) is a drug for the treatment of gout. Gout occurs due to excessive production of uric acid in the body and reduced kidney clearance ability. Uric acid accumulates in the body, leading to the deposition of urate crystals in joints and various organs. Therefore, gout is usually treated by promoting uric acid excretion and inhibiting uric acid production, and taking appropriate measures to improve related symptoms.
Febuxostat is the latest XOR inhibitor developed in the world. It acts on this oxidase highly selectively, reducing the synthesis of uric acid in the body and lowering the concentration of uric acid, thereby effectively treating ventilation diseases. Febuxostat has a significant inhibitory effect on both oxidized and reduced XOR, so its uric acid-lowering effect is more powerful and lasting; this also leads to serious and even fatal adverse reactions due to drug accumulation. Febuxostat is a non-purine XOR inhibitor and therefore has a better safety profile.
A multicenter, double-blind, randomized phase II clinical study evaluated the safety and efficacy of febuxostat in gout. A total of 136 male and 17 female gout patients were randomly assigned to receive placebo or this product (40, 80 or 120 mg/d). After 4 weeks, tests found that the serum uric acid concentration of patients in each dose group of this product was significantly lower than before treatment, with an average reduction of 37% in each group from low to high. %, 44% and 59%, while patients in the placebo group only decreased by 2%; the vast majority of patients persisted in completing the trial. The incidence rates of adverse reactions in this product and the placebo group were similar, and most of these adverse reactions were mild and self-limiting, with common ones including diarrhea, pain, back pain, headache and joint pain.
The therapeutic effect of Febuxostat is remarkable, so where can I buy Febuxostat?
Febuxostat is marketed in many countries. Among them, the Febuxostat marketed in India is more cost-effective and is produced by Zydus Pharmaceuticals in India. Different specifications have different prices. For specific prices, please consult the regular overseas medical service company Medical Travel.
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