The latest prices for a box of different versions of Canafenib announced

Introduction: Canafenib can be used in combination with the MEK inhibitor bimetinib to treat adult patients with metastatic non-small cell lung cancer (NSCLC) with BRAF V600E mutations as detected by an FDA-approved test. On October 11, 2023, the U.S. Food and Drug Administration (FDA) approved the use of this combination therapy. The price of canafenib will vary depending on different factors, including pharmaceutical companies' pricing strategies, drug patent status, market demand, import taxes, etc.

The latest prices for a box of different versions of canafenib are announced

75mg dose, the price of a box of 42 pills is about 15,579$-19,000$, and the price of 75mg dose of Canafenib, the price of a box of 168 pills is about 51,000$-56,000$. Prices are for reference only, actual prices may be affected by a variety of factors. In addition, there are currently no generic drugs of canafenib on the Chinese market, so the price of generic drugs is temporarily unavailable.

Efficacy of canafenib in the treatment of lung cancer

In a pivotal phase II PHAROS trial, canafenib combined with the MEK inhibitor bimetinib showed significant efficacy in the treatment of patients with metastatic non-small cell lung cancer with BRAF V600E mutations. Among treatment-naïve patients, the objective response rate (ORR) was 75%, including a complete response rate (CR) of 15% and a partial response rate (PR) of 59%. Among previously treated patients, the ORR was 46% and the median duration of response (DOR) was 16.7 months.

Safety and tolerability of canafenib

The treatment regimen of canafenib combined with bimetinib has shown good tolerance in clinical trials, but it is also accompanied by some adverse reactions, such as fatigue, nausea, diarrhea, musculoskeletal pain, etc. Serious adverse reactions include bleeding, diarrhea, anemia, dyspnea, etc.

When considering purchasing canafenib, patients should consult professional medical institutions or pharmacies to obtain the latest price information of the drug, and ensure that the drug is purchased through formal channels to ensure the quality and safety of the drug. At the same time, since canafenib is a prescription drug, its purchase and use should be under the guidance of a doctor, and patients are not allowed to take it privately.