罕见病药物氨己烯酸片一个疗程多长时间

Sabril (Vigabatrin) can be used as an auxiliary treatment for partial seizures in refractory complex epilepsy. The starting dose of vigabatrin tablets for adults is 2g per day, divided into 2 times or taken as a single dose. If necessary, increase by 0.5 to 1g, with a maximum dose of 4g per day. Children start taking vigabatrin tablets orally, 40 mg/kg per day, 2 divided doses, and gradually increase to 80 to 100 mg/kg per day if necessary. Adult doses can be given to those weighing more than 50kg. The details are as follows; weight: 10-15Kg 0.5-1g/day; 15-30kg 1-1.5g/day; 30-50kg 1.5-3g/day; >50kg 2-3g/day. The maximum doses listed above should not be exceeded in children of different weights.

Dosage for the elderly and patients with renal impairment: Because vigabatrin tablets are digested by the kidneys, caution should be exercised when the elderly and patients with a creatinine elimination rate less than 60 ml/min (60 ml per minute) take this drug. For both groups, reductions in dosage and frequency should be considered.

How long does it take to take a course of rare disease drug vigabatrin tablets?

It is an oral medicine, which is rapidly absorbed after oral administration, and the peak value of the blood drug can be reached 2 hours after taking it. t1/2 is 5~7h. It is mainly excreted in the urine, and about 65% of the administered dose is excreted in the urine as the original drug within the first 24 hours. Plasma protein binding is not significant. We cannot give a specific time for how long a course of treatment of the rare disease drug vigabatrin tablets lasts. It depends on the patient's own condition. The patient must use the medication under the guidance of a doctor. After taking the medication for a period of time, he or she can go to the hospital for examination.

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