罕见病药物氨己烯酸片的价格是多少
The trade name is Sabril, which was approved for marketing in the United States in August 2009. It is available in tablets and oral solutions and is used to treat epilepsy in infants and adults. Vigabatrin tablets are not on the market in China. The specifications of vigabatrin tablets produced by Sanofi in France are 500mg*100 tablets, and the price is around $1,500.
Vigabatrin tablets are analogs of gamma-aminobutyric acid (GABA), which can specifically bind to GABA aminotransferase and irreversibly, leading to an increase in the concentration of GABA in the brain, thereby exerting anti-epileptic effects. It may also be used in infants with West syndrome (infantile spasms), which is generally unresponsive to conventional antiepileptic drugs. Clinical research results show that vigabatrin is an effective and safe anti-epileptic drug in the treatment of children with severe epilepsy, and is also effective in epilepsy patients with intellectual disabilities.
Vigabatrin tablets are an oral drug that is rapidly absorbed after oral administration and can reach its peak blood level 2 hours after taking it. The maximum daily dosage for adults is 2-3g. It is appropriate to start with 1g a day. Then, depending on the response after taking the medication, if the response is good, it can be increased by 0.5g every week, and finally reaches a dosage of 2-3g per day.
The recommended dosage for children is 40 mg/kg/day. Continuous medication should be judged based on the patient's weight. The recommended dosage for children weighing 10-15kg is 0.5-1g/day; the recommended dosage for 15-30kg is 1-1.5g/day; the recommended dosage for 30-50kg is 1.5-3g/day; >50kg 2-3g/day.
It is a treatment drug for rare diseases. We already have a certain understanding of its efficacy and usage. If it is inconvenient for you to go abroad to purchase this drug, you can consult the Medical Companion Travel Service for specific purchasing methods.
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