喜保宁治疗婴儿痉挛症一般多久见效？制住后会复发吗？

It has anti-epileptic effects, and its mechanism of action is to irreversibly inhibit GABA aminotransferase (GABA-T) and increase GABA concentration in the brain. Clinical research results show that Vigabatrin is an effective and safe anti-epileptic drug for the treatment of children with severe epilepsy, and is also effective for epilepsy patients with intellectual disabilities.

Vigabatrin is absorbed rapidly after oral administration, and food does not affect its absorption rate. Peak plasma concentration is reached 2 hours after taking the drug, t1/2 is 5 to 7 hours, and a single dose of 1 to 3g is taken. The pharmacokinetics show a dose-linear relationship, the apparent volume of distribution is about 0.8l/kg, and the relative bioavailability is 92±11%.

Vigabatrin is suitable for the treatment of refractory partial epilepsy, especially for refractory childhood epilepsy.

How to use Vigabatrin: Orally: For adults and children over 9 years old, the dose is 2g per day, twice a day. It can be increased to 4g per day if necessary. The maximum daily dose is 4g. For children aged 3 to 9 years old, the recommended dose is 1g per day.

Side effects of using Vigabatrin include:

1. Drowsiness, dizziness, headache, fatigue, weight gain, irritability, nervousness, etc. may be seen.

2. Insomnia, nausea, vomiting, ataxia, depression, abnormal behavior (aggressive behavior, etc.), mental confusion, anxiety, etc. are occasionally seen.

How long does it take for Vigabatrin to be effective in treating infantile spasms? Will it relapse after being controlled?

The effective time of using Vigabatrin to treat infantile spasms depends on the condition of the baby. Due to individual differences, the effective time of using Vigabatrin to treat infantile spasms varies from person to person.

Spasticity may relapse after using Vigabatrin to treat spasticity, so pay attention to the baby's condition after use.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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