喜保宁的功效和作用是什么？各种喜保宁版本的区别在哪？

Intractable complex partial seizures (CPS, also known as focal seizures), also known as temporal lobe seizures and psychomotor seizures, manifest partial seizures with varying degrees of consciousness impairment. The U.S. FDA has approved Vigabatrin (vigabatrin tablets) as monotherapy for pediatric patients 1 month to 2 years old, where the potential benefits of infantile spasms outweigh the potential risk of vision loss, and as an adjunctive (additional) treatment (CPS) for adults with refractory complex partial epilepsy. (Vigabatrin tablets) is an effective drug for treating epilepsy. What are the efficacy and functions of this drug? What are the differences between the various Vigabatrin versions?

Efficacy and functions of Vigabatrin (vigabatrin tablets)

Vigabatrin (vigabatrin tablets) is an analog of γ-aminobutyric acid (GABA). It can specifically bind to GABA aminotransferase and irreversibly, leading to an increase in GABA concentration in the brain, thus exerting anti-epileptic effects. Clinically, Vigabatrin (vigabatrin tablets) is used to treat epilepsy in which other anti-epileptic drugs are ineffective, especially partial seizures; Vigabatrin (vigabatrin tablets) can also treat infantile spasms (West syndrome, West syndrome).

Among pediatric patients, 135 children aged 2 months to 12 years old with intractable epilepsy were treated with Vigabatrin (vigabatrin tablets). The effective rate was 34%, of which the effective rate for partial seizures was 49%. The effective rate for generalized seizures was only half of that. There were 13 cases of infantile spasms and 26 cases of Lennox-Gastaut syndrome. Symptomatic childhood spasticity is better treated than cryptogenic spasticity.

The Differences Between Various Vigabatrin Versions

Vigabatrin is sold in different countries or regions, and its specifications or drug prices may be different, but its efficacy, treatment methods, etc. are the same.

Precautions when taking Vigabatrin:

Suicidal ideation may occur during treatment with Vigabatrin: Patients taking antiepileptic drugs are at increased risk for suicidal ideation/behavior. Monitor changes in the patient's behavior and notify the doctor immediately if suicidal thoughts or symptoms of depression occur.

The toxic effects of Vigabatrin on the retina may cause peripheral visual field defects in children, so regular ophthalmological monitoring is required. Vigabatrin should be used under the guidance of an epilepsy specialist or child neurologist. Reactions after taking the medication should be reported to the doctor promptly.

The above is an introduction to Vigabatrin. If patients have other questions about the drug (such as drug prices, purchase channels, etc.), they can consult the medical companion travel service.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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