罕见病药物氨己烯酸片会有副作用吗

Also called Vigabatrin, it is indicated for the treatment of epilepsy in which other anti-epileptic drugs are ineffective, especially partial seizures. It can also treat infantile spasms (West syndrome, West syndrome). It works by irreversibly inhibiting GABA aminotransferase (GABA-T) and increasing GABA concentration in the brain.

Vigabatrin tablets are the drug of choice for TSC epilepsy in foreign countries. In terms of controlling Tsc epileptic seizures, about 95% of children have a good response to vigabatrin tablets. Once a seizure is discovered, regardless of form, vigabatrin tablets can be the first choice, and the effect is better when used for the first time. Especially for infantile spasms (peak arrhythmia in electroencephalogram), vigabatrin tablets should be taken as soon as possible.

Vigabatrin tablets are very effective, but do they have any side effects? Side effects of drugs are basically inevitable during treatment. Common side effects of vigabatrin tablets include fatigue, drowsiness, headache, dizziness, confusion and depression. Occasional aggressive behavior and psychosis (more common in patients with a history of psychosis and behavioral problems), memory loss, diplopia, weight gain, gastrointestinal disturbances, edema, and alopecia. Nystagmus, nervousness, agitation, ataxia, paresthesia, and tremor may also occur.

Vigabatrin tablets can cause permanent vision loss in infants, children, and adults, including progressive and permanent bilateral concentric visual field constriction in >30% of patients, ranging in severity from mild to severe, including tunnel vision to visual acuity fixed within 10 degrees, and can result in disability.

The above are the possible side effects of rare disease drugs. Patients must use the medicine correctly during treatment. If serious side effects occur, please seek medical treatment in time.

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