氨己烯酸片(喜保宁)有什么副作用吗
(Vigabatrin) is a synthetic derivative of gamma-aminobutyric acid (GABA). It increases the concentration of the inhibitory hormonal mediator GABA in the brain by irreversibly inhibiting GABA aminotransferase. In 2009, vigabatrin tablets were approved for marketing in the United States and are mainly used for the treatment of epilepsy in infants and adults.
The usual adult dosage of vigabatrin tablets (Vigabatrin) for the prevention of epileptic seizures is as follows: Initial dosage: 1 g per day (containing 500 mg orally, twice a day, with or without food), the total daily dose may be increased by 500 mg weekly, depending on response. Recommended dose: 3 g orally daily (1.5 g twice daily). The 6 g/day dose did not show additional benefit compared with the 3 g/day dose and was associated with an increased incidence of adverse events. Patients should not increase their dosage without authorization.
Usual pediatric dosage for epilepsy: Infantile spasms: 1 month to 2 years: Initial dose: 50 mg/kg/day of vigabatrin tablets oral solution in two divided doses, with or without food. The dose may be increased in increments of 25 to 50 mg/kg/day every 3 days, up to a maximum of 150 mg/kg/day.
Common side effects of Vigabatrin may include: blurred vision or other eye problems; drowsiness, dizziness, tiredness; problems with walking or coordination; tremors or shaking; aggressive behavior; confusion, thinking or memory problems; weight gain; joint pain; cold symptoms such as stuffy nose, sneezing, sore throat; (in babies) irritability, ear infection, cough, difficulty breathing.
The above are the possible side effects of (Vigabatrin). Patients are asked to follow the doctor's instructions and use the medicine correctly during treatment. If serious side effects occur, please contact the doctor in time.
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