一文解读抗癫痫药司替戊醇的储存和正确服用方法

Introduction: It is an anti-epileptic drug specifically used to treat epileptic seizures related to Dravet syndrome in children 6 months and older (weight 13 pounds or more) taking clobazam. The correct way to store stiripentol is to store it at room temperature. This medicine needs to be taken orally, preferably with food.

Stipentol applicable population

In the United States, the FDA has approved the combination of stiripentol and clobazam for the treatment of epileptic seizures related to Dravet syndrome in patients 6 months of age and older. In other countries, stiripentol is approved in combination with valproic acid and clobazam for the treatment of seizures in Dravet syndrome.

Storage method

Stipentol should be stored at room temperature below 30 degrees Celsius. The medicine should not be exposed to direct sunlight, nor should stiripentol be placed in a humid place to avoid damaging the structure of the medicine, affecting the therapeutic effect or even causing adverse reactions. Keep all medicines out of the reach of children.

Dosage

Patients should take stiripentol exactly as recommended by their doctor. Do not change the dosage without consulting your doctor first, nor should you stop taking the medicine suddenly. Stopping epilepsy medicine suddenly may result in unstoppable epileptic seizures. Stipentol is usually taken 2 to 3 times a day, preferably with food to reduce stomach upset. Capsules should be swallowed whole without opening. For oral powders, follow the instructions for mixing the powder with water, using an accurate measuring spoon or syringe to ensure the correct amount, do not use a regular teaspoon.

Drug Interactions and Missed Doses

Because stiripentol interacts with the way the body breaks down clobazam and fenfluramine, it is usually necessary to reduce the dose of these two drugs when stiripentol is added. If a patient forgets to take medication, he should take it as soon as he remembers it. In order to avoid missing medication, he can set an alarm on his mobile phone or watch to remind him to take medication.

Common side effects

Common side effects of stiripentol are loss of appetite and weight, feeling tired or sleepy, low muscle tone, and loss of balance. In some cases, the above side effects may be caused by high levels of other combination drugs (such as clobazam or valproic acid), as stiripentol reduces the body's ability to metabolize these other drugs.

Stipentol can also cause low white blood cell and platelet counts. It is recommended that blood counts be obtained before starting stiripentol and then at regular intervals.