苯丁酸钠在国内能买到了吗？有什么副作用？

Urea cycle disorder clinically manifests as severe brain dysfunction. It refers to the patient's inability to eliminate ammonia produced by protein decomposition due to a lack of certain enzymes during the urea cycle. Excessive ammonia accumulates in the body and can cause neurotoxicity. It will be launched in China in May 2021 for long-term management of patients with urea cycle disorders, providing a new choice for patients and clinicians.

Is sodium phenylbutyrate available in the country?

After sodium phenylbutyrate is launched on the market, this product can be purchased in domestic hospital pharmacies. However, due to its short time on the market, it has not yet been included in medical insurance. Patients need to pay for this product at their own expense, which imposes a heavy financial burden. Patients can also learn about sodium phenylbutyrate directly shipped from overseas pharmaceutical companies through Medical Companion Travel. The price is affordable and cost-effective, which can reduce the patient's financial burden. Moreover, the medicines will be mailed directly to the patients, which is very convenient and fast. Patients who want to know the specific price and purchase method of sodium phenylbutyrate can consult the medical companion travel service. Drug prices are not fixed due to exchange rate fluctuations. It is not recommended for patients to use purchasing agents as they are easily deceived.

What are the side effects of sodium phenylbutyrate?

Sodium phenylbutyrate is a prodrug that is rapidly metabolized to phenylacetate, which can reduce the frequency of hyperammonemia or hyperammonemic encephalopathy. However, this product also has side effects, including ankle and peripheral edema, constipation, pancreatitis, blood pressure changes, headache, depression, hypoalbuminemia, metabolic acidosis, hypokalemia, hypophosphatemia, hyperphosphatemia, hypernatremia, irregular menstrual cycles in women, and lack of appetite. , nausea, alkalosis, hyperchloremia, hyperuricemia, vomiting, peptic ulcer, rectal bleeding, thrombocytopenia, renal tubular acidosis, elevated alkaline phosphatase levels, etc. are all possible side effects of sodium phenylbutyrate. It is recommended that patients take medication under the guidance of a doctor.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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