托伐普坦的不良反应有什么,饭前吃还是饭后吃?

Tolvaptan is a new type of diuretic that has diuretic effect and can be used to treat hyponatremia caused by syndrome of insufficient secretion of antidiuretic hormone. It is a relatively common drug. It is a vasopressin V2 receptor antagonist that can increase the concentration of sodium ions in plasma and help excess water be excreted from the urine. So, what are the side effects of tolvaptan? Should it be taken before or after meals?

What are the side effects of tolvaptan?

Common ones include frequent urination or polyuria, hyperglycemia, heart failure, liver cirrhosis, thirst, dry mouth, fatigue, constipation, nausea, etc. The process of using tolvaptan tablets can also cause some other side effects, such as atrial fibrillation, diabetic ketoacidosis, etc. It should be noted that this product is not suitable for patients who need to rapidly increase blood sodium. Secondly, it is not suitable for patients who are insensitive to thirst or cannot respond normally to thirst. It is recommended that patients take medication as directed by their doctor, and if they have intolerance, contact their doctor promptly for symptomatic treatment.

Should tolvaptan be taken before or after meals?

Tolvaptan can be taken before or after meals. The usual starting dose for adults is 15 mg once a day. After taking the drug for at least 24 hours, the dose can be increased to 30 mg once a day. Depending on the serum sodium concentration, the maximum dose can be increased to 60 mg, once daily. After the patient stops taking this product, the patient should be instructed to restrict fluid intake again, and changes in serum sodium concentration and blood volume should be detected.

Tolvaptan tablets are highly safe. Only a few patients will experience adverse reactions such as dry mouth, dizziness, hypotension and nausea after taking the drug, but they are not serious and patients can rest assured. Tolvaptan has proven its good efficacy in various PKD animal model studies. There is no need to restrict the patient's drinking water within 24 hours after starting to take tolvaptan. During the entire treatment period, the patient can drink water under the guidance of a doctor when he or she feels thirsty. The above is about the side effects of tolvaptan and whether to take it before or after meals.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

Recommended related articles: