雷帕鸣医保能给报销吗？

Sirolimus is a new type of immunosuppressant developed by Wyeth Company of the United States. Different from tacrolimus, which is a structural homologue, although it acts on the same receptor, its mechanism of action is different. It mainly inhibits the body's immune function by affecting unique cell signaling pathways. In September 1999, the drug was approved by the US FDA and officially launched on the market. It is mainly used to prevent and treat rejection of kidney, liver and other transplants. It is especially suitable for patients with renal dysfunction, tremor and hypertension. The drug has low oral bioavailability, large inter-individual pharmacokinetic (PK) differences, and is a substrate of CYP3A and P glycoprotein (PgP), which can cause drug-drug interactions with a variety of drugs.

Drug prices have always been a concern of patients. So, can Rapamin be reimbursed by medical insurance?

At present, Leipamin has been included in the medical insurance catalog and belongs to the Class B drug of medical insurance. This also means that when patients purchase the drug in China, they can rely on medical insurance to reimburse part of the cost, thereby reducing their out-of-pocket expenses and reducing their own financial burden. Normally, the medical insurance reimbursement ratio is around 70% to 80%. However, it is affected by the medical insurance policies of various regions and other factors, so there will be certain differences in the final reimbursement ratio. Specific patients can consult the relevant departments.

Due to different dosage forms and specifications of rapamin (sirolimus), its usage and dosage may vary. Therefore, patients must carefully read the specific drug instructions or follow the doctor's advice before receiving treatment with this drug. During the actual treatment process, patients should be treated in institutions equipped with appropriate laboratories and auxiliary medical facilities and personnel. It is recommended to use it in combination with cyclosporine and corticosteroids, orally, once a day, regularly with or without food. Since the bioavailability of crushed, chewed, or cut tablets has not been established, such use is not recommended.