吃雷帕鸣期间能拔牙吗
(Alias: sirolimus) was discovered to have immunosuppressive effects in 1977. Judging from the effects of animal experiments and clinical applications, rapamin has good effects and low toxicity. The currently approved indication is to treat patients 13 years of age or older who have received kidney transplants to prevent organ rejection. Recommended for use in combination with cyclosporine and corticosteroids. Compared with cyclosporine, rapamycin requires less dosage to achieve therapeutic effects, has stronger anti-rejection effects, and has fewer side effects.
Kidney transplantation is one of the effective ways to treat end-stage renal disease, and the long-term survival of the organ after transplantation is also a major problem in treatment. Rapamin (sirolimus) is a new type of immunosuppressant that not only has an immunosuppressive effect, but also has a certain targeted therapeutic effect on malignant tumors. In a study, the use of an immunosuppressive regimen based on rapamycin in patients with new malignant tumors after kidney transplantation can achieve stable renal function while controlling or alleviating the progression of malignant tumors.
The effect of rapamin (sirolimus) is relatively good, but we still need to understand some precautions and common sense issues during use. Since taking rapamycin may cause poor wound healing, and immunosuppression may also increase the chance of infection, it is not recommended to extract teeth during this period. It is best for patients to consult their dentist first and decide whether teeth can be extracted based on the dentist's judgment.
(Sirolimus) also interacts with some drugs or foods. For example, grapefruit juice can slow down the metabolism of rapamin regulated by CYP3A4, so it should not be used for administration or dilution of this drug. Patients should read the instructions carefully or follow the doctor's advice before taking the medicine.
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