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For patients undergoing kidney transplantation, it is recommended to be used in combination with cyclosporine and corticosteroids to prevent organ rejection. Rapamin sirolimus tablets inhibit the activation and proliferation of T lymphocytes stimulated by antigens and cytokines (interleukins IL-2, IL-4 and IL-15). It also inhibits the production of antibodies. In cells, rapamycin sirolimus binds to the immunophilin, FK-binding protein-12 (FKBP-12), to generate the FKBP-12 immunosuppressive complex. This complex binds to the mammalian Siros BA molecule (mTOR, a key regulatory kinase) and inhibits its activity, thereby inhibiting the progression from G1 to S phase in the cell cycle.

Patients taking rapamycin sirolimus tablets for treatment should note:

Patients who are allergic to any component of rapamin sirolimus tablets should not use this drug for treatment.

Treatment with rapamin and sirolimus tablets may cause harm to the fetus. Therefore, effective contraceptive measures should be taken during treatment with rapamin and sirolimus tablets and for 12 weeks after stopping. During pregnancy, rapamirumab should be used only if the potential benefits of its use outweigh the potential risks to the embryo/fetus.

Under normal circumstances, patients who have undergone organ transplantation need to pay special attention to their diet. They must eat less salt, sugar and oil, and eat a lighter diet. They can eat more fruits, vegetables and whole grains, which will be easier to digest and will not burden the body.

Treatment with rapamycin sirolimus tablets may cause hyperlipidemia and may increase blood lipids (cholesterol and triglycerides). Patients with hyperlipidemia should use this drug with caution. Patients should monitor cholesterol/lipids while receiving rapamycin sirolimus; if hyperlipidemia occurs, follow current management guidelines (diet, exercise, lipid-lowering agents). Antihyperlipidemic treatments may not be effective in achieving normal levels.

Is it expensive? It is understood that the specifications of rapamirumab sirolimus tablets produced by Biocon Pharmaceuticals in India are 1 mg x 10 tablets, and the price is about $200. Due to factors such as exchange rate fluctuations, the price is not fixed. If patients want to know the specific price information of rapamycin sirolimus tablets, they can consult the medical companion travel service.

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