非布索坦国内上市没呢？

It can effectively treat gout. The successful development of this drug is good news for gout patients. Febuxostat also has unique advantages over other drugs for the treatment of gout. Because allopurinol is a purine analogue, there is no way to avoid the effects of the activities of other enzymes involved in purine and pyridine metabolism during taking the drug. During allopurinol treatment, patients need to take large doses of the drug to maintain high drug levels during treatment.

In a clinical trial study, febuxostat failed to significantly reduce the area of tophi after 52 weeks of treatment, but the effect was more obvious in the high-dose group early in the trial. In each treatment group, patients whose sUA concentration reached the target (<60 mg/L) were less likely to have gout attacks again, and the area of ​​tophi in patients was more significantly reduced. This study data also proves that febuxostat is very effective in treating gout. Some adverse effects may occur with febuxostat, including liver function abnormalities, diarrhea, headache, joint-related signs and symptoms, and musculoskeletal/connective tissue symptoms.

Many patients are concerned: Has febuxostat been launched in the country? Febuxostat was developed in Japan in 2004, approved for marketing by European EMEA in 2008, and approved by the US FDA in 2009. It was approved for marketing by China’s State Food and Drug Administration in 2013. Not only that, Febuxostat has also been included in the national medical insurance, No. 911, the drug name is Febuxostat, the dosage form is oral sustained-release dosage form, the drug category is musculo-skeletal system drugs > anti-gout drugs (XM > XM04), and belongs to Class B of medical insurance. Febuxostat is suitable for gout patients with renal insufficiency or allopurinol allergy. This is also good news for many patients.

However, the price of febuxostat in China is not low, and many patients say it is expensive. According to Medical Travel, Febuxostat produced by Zydus Pharmaceuticals in India has the same efficacy as the original drug, but the price is much cheaper than the original drug, which is affordable for patients. The specification of Febuxostat produced in India is 80mg*30 tablets/box, and its price is about $200. If patients want to buy the Indian version, they can consult Medical Companion Travel.