非布司他可治疗哪些疾病？

What conditions can Febuxostat treat? Febuxostat (alias: febuxostat, feburic) was approved by the U.S. Food and Drug Administration (FDA) in February 2009. Its indication is for the long-term treatment of patients with gout and hyperuricemia.

Gout is caused by the accumulation of uric acid in the body due to the excessive production of uric acid in the body and the reduced ability of the kidneys to remove it, resulting in the deposition of urate crystals in joints and various organs. Currently commonly used clinical uric acid-lowering drugs include drugs that inhibit uric acid production and drugs that promote uric acid excretion. Febuxostat is a drug that inhibits uric acid production and can directly inhibit the activity of xanthine oxidase and reduce the production of uric acid.

The effectiveness of febuxostat (febuxostat, feburic) has been confirmed in clinical trials. The effectiveness of febuxostat in the general population is about 70%, which is higher than that of allopurinol. and significantly higher than the placebo group. Clinical trial data on more than 3,000 people show that febuxostat can effectively reduce uric acid in the blood to 360 μmol/L after taking the drug for six months.

The safety of febuxostat in clinical trials is also relatively good. Most of the adverse reactions are mild and self-limiting. Common ones include back pain, diarrhea, back pain, pain, headache and joint pain.

To effectively exert the effect of febuxostat in treating gout, its correct use is also essential.

Febuxostat (febuxostat, feburic) is a tablet, available in two specifications: 40mg/tablet and 80mg/tablet. Usually, the initial recommended dose for patients is 40 mg/day, administered orally. If the symptoms are severe, it can be adjusted to 80 mg/day; if the serum uric acid level is still higher than 6 mg/dL after 2 weeks of taking 40 mg/day, the dose can be increased to 80 mg/day. It should be noted that febuxostat is not recommended for the treatment of gout patients without hyperuricemia.

The above is an introduction to the indications of febuxostat. I hope it will be helpful to you.