非布司他是哪里产的呢？

Febuxostat (febuxostat, feburic) is a new and highly effective non-purine xanthine oxidase selective inhibitor. Its original drug manufacturer is Teijin Company of Japan. It is clinically used to treat hyperuricemia (gout). It can effectively reduce the uric acid level in the blood of patients with hyperuricemia and gout.

Teijin Corporation of Japan is expanding its business globally in materials, pharmaceuticals, fibers and products, IT, etc. In terms of medicine and medical care, while strengthening and expanding the foundation of pharmaceutical and home medical services, we are also committed to non-medical insurance fields such as nursing care and preventive health care, and develop comprehensive medical and health service services that meet the needs of society.

For 30 years, allopurinol has been the only drug clinically used to inhibit uric acid production. Compared with allopurine, febuxostat also has very obvious advantages. Unlike allopurinol, which only inhibits the reduced form of XOR, febuxostat also has a significant inhibitory effect on the oxidized form of XOR, so its uric acid-lowering effect is more powerful and lasting. And febuxostat is also safer.

It should be noted that in the early stage of taking febuxostat (febuxostat, feburic), due to the rapid decrease in serum uric acid concentration, the uric acid deposited in the tissues can be mobilized. To avoid this, nonsteroidal anti-inflammatory drugs or colchicine can be used for preventive administration. Cardiovascular thrombotic events are more likely to occur with febuxostat, and patients should be monitored for signs and symptoms of myocardial infarction (MI) and stroke after initiating treatment.

As we all know, the price of original drugs is relatively high. In addition to the generic drugs developed by Teijin Corporation of Japan, the generic version of febuxostat (febuxostat) has also been launched in India. The manufacturer is Zydus Pharmaceuticals. The efficacy is the same as the original drug, but the price is relatively low. The specification is 80mg*30 tablets/box, and the price is around 200$. Due to exchange rate fluctuations, the price may fluctuate.