静脉血栓治疗药物利伐沙班副作用有哪些?
(Xarelto) is a highly selective, oral drug that directly inhibits factor xa. By inhibiting factor xa, the endogenous and exogenous pathways of the coagulation cascade can be interrupted, and the generation of thrombin and thrombosis can be inhibited. Rivaroxaban is a red film-coated tablet used clinically for the prevention of venous thrombosis (VTE) in adult patients undergoing elective hip or knee replacement surgery. Today we will learn more about the side effects of venous thrombosis treatment drug rivaroxaban?
Rivaroxaban (Xarelto) side effects 1-10%: abdominal pain, back pain, contusion, constipation, diarrhea, oropharyngeal pain, osteoarthritis, peripheral edema, dizziness, indigestion, headache, nausea, hematuria, muscle cramps, pruritus, epistaxis, fatigue, fever, rash, syncope, toothache, urinary tract infection (≤1%), vomiting, wound discharge. Atrial fibrillation (6% major bleeding), DVT prophylaxis (5-6%; major bleeding <1%), DVT treatment (6-10%; major bleeding 1%), hematoma (<3%). Rivaroxaban (Xarelto) side effects <1%: dysuria, fatal bleeding, hypotension, increased amylase, hematoma, hemiparesis, bleeding, increased BUN, jaundice, menorrhagia, drug reaction with eosinophilia and systemic symptoms (DRESS), urticaria, thrombocytopenia, xerostomia.
Rivaroxaban (Xarelto) side effects post-marketing or case reports: Agranulocytosis, anaphylactic shock, anaphylaxis, angioedema, intracerebral hemorrhage, cholestasis, decreased hemoglobin, DRESS syndrome (with eosinophilia) and systemic symptoms (drug eruption), injection site hematoma, hemiplegia, hematuria, intracranial hemorrhage, jaundice, retroperitoneal hemorrhage, spinal hematoma, hepatitis, liver injury, allergic reaction, subdural hematoma, Stevens-Johnson syndrome, thrombocytopenia.
Adverse reactions are inherent effects of the drug itself and vary depending on the purpose of the treatment. Most of them are mild and disappear after stopping the drug. If you have mild side effects of Rivaroxaban (Xarelto), you can decide whether to continue taking the medication based on your own situation. If you have serious side effects, you should inform your doctor or pharmacist as soon as possible.
The above is the content of the adverse reactions of (Xarelto), I hope it can help you!
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