拜瑞妥常见不良反应有哪些呢？

Rivaroxaban Tablets (rivaroxaban) is a highly selective, oral drug that directly inhibits factor XA. Rivaroxaban is approved for the prevention of venous thrombosis (VTE) in adult patients undergoing hip or knee replacement surgery; and the treatment of deep vein thrombosis (DVT) in adults to reduce the risk of DVT recurrence and pulmonary embolism (PE) after acute DVT.

What are the common adverse reactions of Xarelto?

1-10%: abdominal pain, back pain, contusion, constipation, diarrhea, dizziness, indigestion, epistaxis, fatigue, headache, nausea, hematuria, muscle spasm, oropharyngeal pain, osteoarthritis, peripheral edema, pruritus, fever, rash, syncope, toothache, urinary tract infection (≤1%), vomiting, wound discharge. Atrial fibrillation (6% major bleeding), DVT prophylaxis (5-6%; major bleeding <1%), DVT treatment (6-10%; major bleeding 1%), hematoma (<3%).

<1%: dysuria, fatal hemorrhage, hematoma, hemiparesis, hemorrhage, hypotension, increased amylase, increased BUN, jaundice, menorrhagia, drug reaction with eosinophilia and systemic symptoms (DRESS), thrombocytopenia, urticaria, xerostomia.

  Rivaroxaban tablets () post-marketing or case reports: agranulocytosis, anaphylactic shock, anaphylaxis, angioedema, cerebral hemorrhage, cholestasis, hemoglobin drop, DRESS syndrome (drug rash with eosinophilia and systemic symptoms), injection site hematoma, hemiplegia, hematuria, hepatitis, liver injury, allergic reaction, intracranial hemorrhage, jaundice, retroperitoneal hemorrhage, spinal hematoma, Stevens-Johnson syndrome, subdural hematoma, thrombocytopenia.

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