长期吃利伐沙班的副作用

(Rivaroxaban) is a new oral anticoagulant drug jointly developed by Bayer and Johnson & Johnson. It is also a highly selective and competitive drug that directly inhibits factor Xa. Patients can obtain considerable therapeutic effects by insisting on taking this drug, but during long-term use of this drug, the drug will also produce some side effects, which patients need to pay attention to.

1. The most common adverse reaction of taking rivaroxaban is bleeding, which manifests as nose bleeding, gum bleeding, gastrointestinal bleeding (vomiting blood, bloody stools), hematuria, intracranial bleeding, etc. Other adverse reactions include nausea, abdominal pain, elevated liver enzymes, cholestasis, sinusitis, limb pain, urinary tract infection, etc.

In order to prevent bleeding, we must first actively improve some correctable risk factors for bleeding, such as good blood pressure control, regular evaluation of renal function, and minimizing combined use of drugs (such as antiplatelet drugs and nonsteroidal anti-inflammatory drugs, etc.). If there is an unexplained decrease in hemoglobin or blood pressure, the bleeding site should be searched; if severe bleeding or acute renal failure occurs, this drug should be discontinued.

3. Rivaroxaban may also cause other side effects. If the patient finds any problems while taking the medicine, please seek medical attention in time.

In addition, during treatment with rivaroxaban (i.e. Xarelto), patients should pay attention to: renal function should be monitored before taking the drug, and then monitored at least once a year, including liver function, blood routine, etc. Patients with abnormal renal function need to monitor renal function every 3 months or half a year. This medicine should be taken with food, because food can increase the efficacy of rivaroxaban. If you have difficulty swallowing and the whole tablet is difficult to swallow, you can crush the medicine and mix it with food before taking it. It will not affect its efficacy. If you stop taking it too early, it may cause thromboembolism, so you must take the medicine under the guidance of a doctor and do not stop the medicine without authorization.

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