他克莫司有哪几个版本?分别多少钱?

Tacrolimus capsule is a calcineurin inhibitor immunosuppressant. It is suitable for preventing organ rejection in kidney transplant patients. It needs to be used in combination with other immunosuppressants (such as mycophenolate mofetil and corticosteroids). It is suitable for adult and pediatric patients who can swallow the capsule intact. This article will detail the different versions of tacrolimus, their price information, and clinical efficacy, aiming to provide patients with comprehensive and accurate information.

What versions of tacrolimus are there

Capsule dosage forms

Tacrolimus mainly exists in the form of capsules, including immediate-release capsules and sustained-release capsules. Among them, capsules are the most common dosage form on the market and are widely used in clinical practice.

Different trade names

In addition to tacrolimus capsules produced by Japan's Towa Pharmaceutical, there are many other trade names such as ASTAGRAFXL, Tacrolimus, Prograf, etc. These trade names represent different preparations or brands of the same active ingredient.

Generic drugs

With the expiration of patents, a variety of generic drugs of tacrolimus have appeared on the market, providing patients with more choices.

How much do the different versions of tacrolimus cost?

Japanese Towa Pharmaceutical version

The price of tacrolimus capsules (specification: 0.5mg*100 tablets/box) produced by Japan Towa Pharmaceutical is approximately US$110. This price reflects the quality assurance of the original drug and the high research and development costs.

Price of generic drugs

Compared with original drugs, generic drugs usually have a more affordable price. In the Chinese market, due to the participation of multiple companies, the price of generic drugs may be lower than that of original drugs. The specific price varies depending on manufacturers and regional policies.

Medical insurance reimbursement status

In China, tacrolimus has been included in the scope of medical insurance reimbursement, and eligible patients can enjoy a certain percentage of cost reductions, reducing the financial burden on patients.

The efficacy of tacrolimus

Indications

Tacrolimus is mainly used to prevent organ rejection in kidney transplant patients and needs to be used in combination with other immunosuppressants. In addition, it is also suitable for adult and pediatric patients who are able to swallow the capsule intact.

Mechanism of action

Tacrolimus is a calcineurin inhibitor immunosuppressant that reduces the body's immune response by inhibiting the activation of T lymphocytes, thereby preventing organ rejection.

Long-term effects

Research shows that the rational use of tacrolimus can not only significantly improve the success rate of transplantation, but also prolong graft survival time. At the same time, it also performs well in the treatment of certain autoimmune diseases. However, blood levels need to be monitored closely to avoid adverse effects.