What does azathioprine treat? Can azathioprine be taken long-term?

What does azathioprine treat? Imulan tablets can be used in combination with corticosteroids and/or other immunosuppressants and treatments to prevent rejection in patients with organ transplants (kidney transplants, heart transplants and liver transplants) and reduce the need for corticosteroids in kidney transplant patients. This product is usually used in combination with corticosteroids and/or other immunosuppressants and therapeutic measures or alone, and can achieve clinical efficacy (including corticosteroid reduction) in the treatment of the following patients: severe rheumatoid arthritis; systemic lupus erythematosus; dermatomyositis; autoimmune chronic active hepatitis; polyarteritis nodosa; autoimmune hemolytic anemia; spontaneous thrombocytopenic purpura.

Can azathioprine be taken long-term? Azathioprine is a type of immunosuppressant that inhibits lymphocytes in the human body. Although the effect of azathioprine is good, if the patient feels that his condition has recovered after taking the medicine for a period of time, he should gradually reduce the dosage of the medicine under the guidance of a professional doctor until it is discontinued. Do not blindly take azathioprine tablets for a long time.

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Organ Transplantation Dosage - Adults and Children:

First-day dose: The dosage of this product depends on the immunotherapy regimen used. Usually the first-day dosage is up to 5 mg per kilogram of body weight per day.

Maintenance dose: The maintenance dose should be adjusted according to clinical needs and blood system tolerance. It is generally 1 to 4 mg per kilogram of body weight per day.

Therapeutic dosage for other diseases - adults and children: Under normal circumstances, the starting dose of this product is 1 to 3 mg/kg/day. During the continued treatment, the dosage will be adjusted accordingly within this range according to the clinical response (there may be no response for months or weeks) and the tolerance of the blood system. When the therapeutic effect is obvious, the dosage should be considered to be reduced to the lowest dose that can maintain the therapeutic effect as a maintenance dose. If the condition does not improve within 3 months, discontinuation of this product should be considered.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.