磷酸二甲酯片(Astomin)的副作用如何缓解

The main component of Astomin is dimethyl phosphate. Since it was launched in Japan in 1974, it has been widely used in clinical applications.

Side Effects of Dimethyl Phosphate Tablets (Astomin)

According to the drug instructions, the following side effects may occur in some patients, with varying incidence rates. Close observation is required during medication.

1. Allergic reaction

(1) Symptoms: rash and other allergic manifestations.

(2) Incidence: The frequency is unknown. Although it is rare, we still need to be vigilant.

2. Psychological nervous system

(1) Common symptoms (incidence rate 1%~5%): dizziness, drowsiness, headache or heavy head.

(2) Rare symptoms (incidence <0.1%): fatigue and burnout.

3. Digestive system or cardiovascular system

(1) Common symptoms (1%~5%): dry mouth, loss of appetite, nausea, vomiting, diarrhea.

(2). Rare symptoms (<0.1%): tachycardia, palpitations, facial flushing.

The pictures are from public channels (such as the official website of the FDA, the official website of the original drug manufacturer, etc.) and are for reference only.

Methods for alleviating and dealing with the side effects of dimethyl phosphate tablets (Astomin)

If the above side effects occur during taking the medicine, the following measures can be taken to alleviate or deal with them:

1. Self-care suggestions for mild side effects

(1), dizziness and drowsiness: avoid driving or operating machinery, and try to take the medicine at rest.

(2) Dry mouth: Drink an appropriate amount of water or use sugar-free throat lozenges to relieve it.

(3) Nausea and loss of appetite: It is recommended to take the medicine after meals to reduce gastrointestinal irritation.

2. Situations that require medical treatment

If the following conditions occur, you should stop taking the medicine immediately and consult a doctor:

Skin rash and other allergic symptoms.

Persistent or worsening dizziness and palpitations.

Severe gastrointestinal reactions (such as frequent vomiting, diarrhea).

3. Drug misuse warning

You need to take the tablets out of the aluminum foil plate before taking it to avoid swallowing the whole plate, which may cause damage to the esophageal mucosa or even perforation.

Precautions for use of Dimethyl Phosphate Tablets (Astomin) in special populations

Patients with different physiological states or suffering from specific diseases need to be extra cautious when using this product.

1. Diabetic patients

Dimethyl phosphate may cause mild changes in glucose tolerance, so blood sugar needs to be monitored.

2. Pregnant women

It should only be used when the benefits of treatment outweigh the potential risks and should be decided after a doctor's evaluation.

3. Breastfeeding women

Should consider the benefits of breastfeeding and the potential effects of medications to decide whether to continue breastfeeding or discontinue medication.

4. Elderly people

Physiological functions usually decline. It is recommended to reduce the dosage as appropriate and observe the reaction closely.

Drug characteristics of Astomin tablets

1. Non-narcotic antitussive treatment

Dimethyl phosphate tablets have no drug dependence and are suitable for patients who require long-term cough relief.

2. Effective antitussive effect

Especially for coughs caused by acute respiratory infections.

3. Little impact on intestinal function

Compared with codeine, it is less likely to cause constipation and is suitable for people with intestinal sensitivity.