盐酸缬更昔洛韦片价格多少钱一盒？

It is the L-valyl ester (prodrug) of ganciclovir. After oral administration, it is rapidly converted into ganciclovir by esterases in the small intestine and liver. Ganciclovir is a synthetic analog of 2’-deoxyguanosine that inhibits herpes virus replication in vitro and in vivo. Susceptible human viruses include human cytomegalovirus (HCMV), herpes simplex virus-1 and herpes simplex virus-2 (HSV-1, HSV-2), human herpesvirus-6, 7, 8 (HHV-6, 7, 8), Epstein-Barr virus, varicella-zoster virus (VZV), and hepatitis B virus. In cells infected with cytomegalovirus (CMV), ganciclovir is first phosphorylated by the viral protein kinase UL97 to ganciclovir monophosphate. It is further phosphorylated by intracellular protein kinases into ganciclovir triphosphate, which is then slowly metabolized within the cell. After removal of extracellular ganciclovir, the half-life of ganciclovir in HSV- or HCMV-infected cells is 18 hours and 6 to 24 hours, respectively. Since phosphorylation is largely dependent on viral protein kinases, ganciclovir phosphorylation occurs preferentially in virus-infected cells.

The safety and efficacy of valganciclovir hydrochloride tablets treatment were verified in two different trials: The antiviral effect of valganciclovir hydrochloride tablets was clinically confirmed by treating AIDS patients with newly diagnosed retinitis (clinical study WV15376).

The detection rate of CMV virus decreased from 46% (32/69) to 7% (4/55) after 4 weeks of treatment with valganciclovir hydrochloride tablets, and the U.S. Food and Drug Administration (FDA) approved the increased use of valganciclovir hydrochloride in adult kidney transplant patients at high risk for cytomegalovirus (CMV) disease. The supplemental approval is based on data that longer-term prophylactic treatment with valamciclovir hydrochloride reduced the incidence of CMV disease in high-risk adult kidney transplant patients from 36.8% (for patients treated for 100 days) to 16.8% (for patients treated for 200 days) one year after receiving a kidney transplant) (p <0.0001).1.2 The overall safety profile of valamciclovir hydrochloride does not change when prophylaxis is extended in high-risk renal transplant patients.

After the editor has taken you through the therapeutic effects of Valganciclovir Hydrochloride Tablets, then we come to the question of the price of a box of Valganciclovir Hydrochloride Tablets. According to the editor of Medical Companion Travel, Roche's (valgansiklovir) 450mg*60 tablets sell for about RMB 5,500 in Indian pharmacies. Since the exchange rate fluctuates and the price is not fixed, please contact Medical Travel for details.