Are there any side effects of deflazacort in treating Duchenne muscular dystrophy? What should I pay attention to?

The third-generation glucocorticoid deflazacort is indicated for the treatment of Duchenne muscular dystrophy (DMD) in adults and children at least 2 years of age. The drug has anti-allergic, anti-inflammatory, and increased gluconeogenesis effects, which can improve muscle strength and slow down the progression of disability. Today we will learn more about the side effects of treating Duchenne muscular dystrophy? What should I pay attention to?

Although deflazacort has good therapeutic effects, it also has side effects. Weight gain, increased appetite, upper respiratory tract infection, cough, frequent urination, etc. are common side effects of this drug. Some uncommon side effects include runny nose or nasal congestion, excess hair growth, central obesity, irritability, abdominal discomfort, eye diseases; gastrointestinal diseases; thirst; infections: stye, impetigo, influenza, external ear infection, sore throat, tooth abscess, urinary tract infection (UTI), viral infection, etc. Patients should pay attention to their own reactions during medication, and if they are intolerant, contact their doctor promptly and adopt a new treatment plan.

What should I pay attention to during deflazacort treatment? Patients receive all immunizations according to immunization guidelines before treatment; administer attenuated or live vaccines at least 4-6 weeks before starting treatment. This drug is contraindicated in systemic infectious diseases. Deflazacort should be used with caution in patients with diverticulitis, recent gastrointestinal surgery, renal failure, hypertension, diabetes, osteoporosis, myasthenia gravis; the drug may produce or cause other adverse effects on breast milk. Patients must follow the doctor's instructions to take medication and treat symptoms accordingly, and should not use it in a hurry to avoid affecting the original condition.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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