氨己烯酸片(喜保宁)从哪里能买到

The generic name of Vigabatrin, trade name Sabril, is a drug used to treat epilepsy and infantile spasms, developed in the 1980s. Vigabatrin tablets were approved for marketing in the UK in 1989. On August 21, 2009, the US FDA approved the drug as a monotherapy for the treatment of pediatric patients aged 1 month to 2 years old. The potential benefits of infantile spasms outweigh the potential risk of vision loss and as an adjuvant (additional) treatment (CPS) for adult patients with refractory complex partial epilepsy.

Although Vigabatrin tablets (Vigabatrin) have been on the market abroad for many years, they have not been on the market in China. Therefore, patients who want to purchase this drug can only choose the overseas version. It is understood that the specifications of vigabatrin tablets produced by France's Sanofi are 500mg*100 tablets, and the price is around 1,500$. The price may change due to various factors such as exchange rates. Patients can consult the medical companion travel service for specific prices and formal purchasing methods.

After purchasing Vigabatrin tablets, patients must use them in the correct way. Among them, the maximum daily dose for adults is 2-3g. It is appropriate to start taking it with 1g a day. Then according to the response after taking the medication, if the response is good, it can be increased by 0.5g every week, and finally reaches a dose of 2-3g per day. The recommended dose for children is 40 mg/kg/day. Continuous medication should be judged based on the patient's weight. The recommended dose for patients weighing 10-15 kg is 0.5-1g/day; the recommended dose for 15-30 kg is 1-1.5 g/day; the recommended dose for 30-50 kg is 1.5-3g/day; and >50 kg, the recommended dose is 2-3g/day. 

Vigabatrin can cause permanent vision loss in infants, children, and adults, including progressive and permanent bilateral concentric visual field constriction in >30% of patients, ranging in severity from mild to severe, including tunnel vision to visual acuity fixed within 10 degrees, and can lead to disability.

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