赛诺菲的喜保宁功效和作用

Vigabatrin is a racemic gamma-aminobutyric acid (GABA) analogue, and its (S) enantiomer has pharmacological activity. It inhibits the catabolism of γ-aminobutyric acid by irreversibly inhibiting γ-aminobutyric acid transaminase, thereby increasing the level of γ-aminobutyric acid in the brain and achieving anti-epileptic therapeutic effects.

Vigabatrin is clinically used for the treatment of infantile spasms between one month and two years old; in addition, it is used as an adjuvant therapy for the treatment of refractory complex partial seizures (CPS) in adults. Clinical trials have shown that Vigabatrin has the risk of causing patients' visual field narrowing and permanent blindness; in adult patients, common adverse reactions include drowsiness, headache, etc., and in infant patients, it manifests as hyperactivity.

So far, Vigabatrin is the only drug approved by the FDA for the treatment of infantile spasms. It was launched in the United States in the fourth quarter of 2009, opening up broad prospects for the treatment of infantile spasms.

The recommended dose of Vigabatrin is 3g per day, taken in divided doses. The dose should be increased according to the clinical effect at a rate of 0.5-1g per day to 4g per day (or 50mg/kg per day), which is effective for complex partial seizures of epilepsy (with or without generalized tonic-clonic seizures).

Currently on the market more patients are keen on Sanofi's. Sanofi (NYSE: SNY) was founded in 1973. Its predecessor was Sanofi-Aventis. It was changed to its current name: Sanofi in May 2011. It is headquartered in Paris, France, and has 113,496 full-time employees in more than 100 countries around the world. It is the world's leading diversified pharmaceutical and health company with diversified products, including drugs, vaccines and innovative treatment solutions. According to Medical Companion Travel, the specification of Sanofi Vigabatrin is 500mg*100 capsules/box, and the price is equivalent to RMB 1,450. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about Vigabatrin, please contact Medical Companion Travel for details.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.