抗癫痫新药呲仑帕奈在中国上市了吗?
Perampanel is a noncompetitive alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptor antagonist. Perampanel is approved as an adjunctive treatment for focal epilepsy with or without secondary generalized epilepsy in patients 12 years of age or older in more than 55 countries, including Australia, North America, Europe, Asia and Russia. Perampanel is also approved as adjunctive therapy for primary generalized tonic-clonic (PGTC) seizures in patients 12 years of age and older in North America, Europe, Asia and Russia.
Studies in preclinical epilepsy models and clinical evidence indicate that perampanel has anti-epileptic potential and is well tolerated and effective against primary generalized seizures and other focal seizures, with or without secondary generalization. Furthermore, there is extensive clinical experience with perampanel in real-world patients. Of note, perampanel has not been shown to exacerbate other types of seizures, such as absence or myoclonic seizures.
Most patients experience only mild side effects from perampanel. Common symptoms include dizziness, drowsiness, headache, fatigue, irritability, nausea and falls, and most are mild to moderate. If side effects occur, you need to contact your doctor. Side effects will be reduced when the dosage titration is slowed down and the dosage of concomitant medications is adjusted. Patients should remember to stop taking medication or adjust dosage without permission.
Have new anti-epileptic drugs been launched in China? Perampanel was approved for sale in China on September 29, 2019, and has now been included in the national medical insurance to provide everyone with government discounts to reduce their financial burden. But even after medical insurance, the price of parampanel remains high, prohibiting many families. However, according to Medical Companion Brigade, parampanel is more suitable for long-term use by patients and more cost-effective than other versions. Since the exchange rate has been in a state of fluctuation for a long time, the price fluctuates with the exchange rate and is not static. For more information about Parapanel, please contact Medical Companion Travel for details.
Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.
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