氨己烯酸片在哪里可以买到？

Vigabatrin is an irreversible GABA transaminase inhibitor that can increase the level of GABA in the brain and cerebrospinal fluid. It was developed in the 1980s. In 1989, the vigabatrin tablet Vigabatrin was approved in the UK. On August 21, 2009, the U.S. FDA approved Vigabatrin as a monotherapy for pediatric patients aged 1 month to 2 years old, where the potential benefits of infantile spasms outweigh the potential risk of vision loss, and as an adjuvant (additional) treatment for adult patients with refractory complex partial epilepsy (CPS). On January 16, 2019, the FDA approved the launch of a generic version of Vigabatrin, a generic version of vigabatrin tablets. Vigabatrin tablets are sold under the brand name Sabril in Canada, Mexico and the United Kingdom.

In the trial, 25 children were treated with vigabatrin tablets and vigabatrin to observe the efficacy and safety of the drug. The results showed that 2 months after taking the medicine, the total effective rate was 68.0%. A total of 24 cases took the medicine for ≥4 months, and the total effective rate was 70.8%. After taking vigabatrin tablets Vigabatrin, the blood concentration of phenobarbital is lower than the pre-medication level. The serum alanine aminotransferase level was lower than before taking the drug.

In terms of safety, 22 of the children who received treatment had no side effects; 2 cases developed symptoms of mild dizziness and drowsiness early after taking the drug, but these symptoms could be relieved by themselves; 1 case developed severe restlessness and terminated treatment. From experiments, we can see that vigabatrin tablets Vigabatrin have a good effect on children with refractory epilepsy, and children have good tolerance to it. 

In foreign literature, the therapeutic dose of vigabatrin tablets is 0.10 to 0.15g/(kg·d), which generally takes effect 2 weeks after the initial treatment, manifested by the reduction or disappearance of convulsive attacks and the disappearance of peak arrhythmia-like EEG. Patients need to follow the doctor's instructions carefully while taking the medication and do relevant examinations. The toxic effects of vigabatrin tablets on the retina may cause peripheral visual field defects in children, so regular ophthalmological monitoring is required.

Where can I buy it? It is understood that vigabatrin tablets are only available in a few countries, and the vigabatrin tablets (vigabatrin) produced by Sanofi in France are cost-effective. Its specifications are 500 mg

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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