氨己烯酸片在国内药店有卖吗？

Vigabatrin is a structural analog of gamma-aminobutyric acid (GABA). It inhibits the catabolism of GABA by irreversibly inhibiting GABA transaminase, thereby increasing the concentration of GABA in the brain and achieving anti-epileptic therapeutic effects. The vigabatrin tablet Vigabatrin was actually approved for marketing in the UK as early as 1989. It was not until 2009 that the US Food and Drug Administration (FDA) approved Vigabatrin for the treatment of infantile spasms and refractory focal epilepsy, making it one of the first-choice drugs for the treatment of infantile spasms, especially for patients with tuberous sclerosis.

Vigabatrin tablets are the drug of choice for TSC epilepsy in foreign countries. In terms of controlling Tsc epilepsy, about 95% of children have a good response to vigabatrin tablets. Once a seizure is discovered, regardless of form, vigabatrin tablets can be the first choice, and the effect is better when used for the first time. Especially for infantile spasms (peak arrhythmia in electroencephalogram), vigabatrin tablets should be taken as soon as possible. 

Are vigabatrin tablets sold in domestic pharmacies? Vigabatrin tablets are not marketed in China, so patients cannot purchase the drug in domestic pharmacies.

Vigabatrin vigabatrin tablets need to be used under the guidance of a doctor with experience in treatment. The recommended dose of vigabatrin tablets vigabatrin is as follows: the maximum daily dose for adults is 2-3g, and 1g a day is appropriate when starting to take it. Then based on the response to the medication, if the response is good, it can be increased by 0.5g per week, and finally reaches a dose of 2-3g per day.

The recommended dosage for children is 40 mg/kg/day. Continuous medication should be judged based on the patient's weight. The recommended dosage for children weighing 10-15kg is 0.5-1g/day; the recommended dosage for 15-30kg is 1-1.5g/day; the recommended dosage for 30-50kg is 1.5-3g/day; >50kg 2-3g/day. If the patient has special circumstances, he or she needs to inform the doctor before starting treatment with Vigabatrin Tablets. The doctor will make adjustments to the patient's medication based on the actual situation to avoid harm to the patient due to incorrect medication.

The incidence of visual field defects is high (approximately one third) in patients taking vigabatrin tablets Vigabatrin. This often occurs after several months to several years of using Vigabatrin. Visual field defects can be severe, which can have real consequences for the patient. Most patients with visual field loss have no obvious symptoms.

The above is an introduction to Vigabatrin. If patients have other questions about the drug (such as drug prices, purchase channels, etc.), they can consult the medical companion travel service.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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