氨己烯酸进入医保了吗？

Is vigabatrin included in medical insurance? Vigabatrin is not marketed in China, nor is it included in the medical insurance catalog. It is understood that Vigadrone is only available in a few countries, and Vigadrone produced by Sanofi in France is cost-effective. Its specifications are 500mg

Vigabatrin is an irreversible GABA transaminase inhibitor that can increase the level of GABA in the brain and cerebrospinal fluid. It was developed in the 1980s. In 1989, the vigabatrin tablet Vigabatrin was approved in the UK. On August 21, 2009, the U.S. FDA approved Vigabatrin, a vigabatrin tablet, for monotherapy in children aged 1 month to 2 years old. The potential benefits of infantile spasms outweigh the potential risk of vision loss, and as an adjuvant (additional) treatment (CPS) for adult patients with refractory complex partial epilepsy. On January 16, 2019, the FDA approved the launch of a generic version of Vigabatrin, a generic version of vigabatrin tablets.

In foreign literature, the therapeutic dose is 0.10~0.15g/(kg·d), which usually takes effect 2 weeks after the initial treatment, manifested by the reduction or disappearance of convulsive attacks and the disappearance of peak arrhythmia-like EEG. Patients need to follow the doctor's instructions carefully while taking the medication and do relevant examinations. The incidence of visual field defects in patients treated with vigabatrin is high (approximately one third). This often occurs after several months to years of using vigabatrin. Visual field defects can be severe, which can have real consequences for the patient. Most patients with visual field loss have no obvious symptoms. In adult patients, peripheral neuropathy has occurred after treatment with vigabatrin, manifested by numbness or tingling in the toes or feet, diminished vibration or position sensation, or progressive loss of reflexes in the distal lower extremities. Patients taking the antiepileptic drug vigabatrin are at increased risk for suicidal ideation/behavior. Monitor changes in the patient's behavior and notify the doctor immediately if suicidal thoughts or symptoms of depression occur.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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