呲仑帕奈治疗癫痫的效果特别好吗？

Epilepsy is the most common neurological disease in children, with a prevalence rate of 3% to 9%. About 1/3 of patients are still difficult to effectively control their condition after standard anti-epileptic drug treatment, and these patients are classified as "refractory epilepsy." At present, there is no unified diagnostic standard for "refractory epilepsy" at home and abroad. It is a third-generation new anti-epileptic drug. After its launch, it has been used in many countries to treat various types of refractory epilepsy in children, and has achieved good results. So, is parampanel particularly effective in treating epilepsy?

For children aged 12 to 18 years old with refractory epilepsy, parampanel can significantly reduce the frequency of epileptic seizures compared with placebo. One study conducted a retrospective analysis of 6 randomized, double-blind phase II and phase III studies, evaluating at least 346 children aged 12 to 17 years with refractory epilepsy. Compared with the placebo group (median attack rate reduction of 18.0% every 28 days), the efficacy advantage of the garampanel 8 mg/d group (35.9%) and the 12 mg/d group (53.8%) was statistically significant, and the safety profile was similar to that of adults. The results reveal that add-on treatment with valampanel can better control epileptic seizures and has a good safety profile. For the treatment of children with refractory epilepsy aged 4 to 12 years old, relevant studies have shown that parampanel has the same effectiveness, safety and tolerability as in phase III clinical trials.

Observed in the experiment were irritability, dizziness, headache, fatigue, nausea, drowsiness, falls, etc. If you are currently using Parampanel, the editor here recommends that patients must take the correct medication according to the doctor's instructions. Some patients always think that simply increasing the dose of the drug can improve the effect of the drug itself, and they also think that simply reducing the dose of the drug can reduce the occurrence of side effects. However, this is not actually the case. If the dose of the drug is changed privately, it may cause more adverse reactions, so do not use the drug blindly.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.