氯巴占（Frisium）的功效与作用是什么？

Clobazam (Frisium) is classified as a second-category controlled psychotropic drug. It is an organic compound suitable for the treatment of refractory epilepsy that is ineffective with other anti-epileptic drugs. Sedation has minimal side effects and is more suitable for auxiliary treatment of epilepsy in adults. Today let’s take a closer look at the functions and functions of Clobazam (Frisium)?

Clobazam is a long-acting benzodiazepine that is suitable for the treatment of anxiety disorders and refractory epilepsy. It is more effective in treating complex epileptic seizures secondary to generalized seizures and Lung-Chiari syndrome. This drug is a broad-spectrum anti-epileptic drug that can cause drug dependence. Clobazam can be used alone or as an auxiliary treatment. After clobazam (Frisium) enters the body, it is absorbed quickly and the effect is very good. Trials have shown that clobazam was used in two multi-center controlled studies involving children aged ≥2 years. The patients' seizure control improved after taking this product, and their anxiety and convulsions were also significantly improved.

Clobazam is easily absorbed after oral administration, 85% is bound to plasma proteins, and the peak plasma dose can be reached in 1 to 4 hours. The drug is highly lipophilic and quickly penetrates the blood-cerebrospinal fluid barrier. It was approved for marketing in the European Union in May 2013. Clobazam has anti-anxiety and anti-convulsant effects, and its ED50 for anti-electroshock is smaller than that of diazepam but larger than that of phenobarbital and sodium valproate. Patients should note that it is contraindicated in those who are allergic to clobazam, pregnant women, and breast-feeding patients. Clobazam (Frisium) is effective for both partial and generalized seizures in patients with epilepsy caused by different causes, but is usually used as an auxiliary drug.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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