法国赛诺菲的氨己烯酸有哪些副作用？

French Sanofi has anti-epileptic effects. Its mechanism of action is to irreversibly inhibit GABA aminotransferase (GABA-T) and increase the concentration of GABA in the brain to exert its effects. Clinical research results show that vigabatrin is an effective and safe anti-epileptic drug in the treatment of children with severe epilepsy, and is also effective in epilepsy patients with intellectual disabilities.

France's Sanofi Vigabatrin is rapidly absorbed after oral administration, and food does not affect its absorption speed. Peak plasma concentration is reached 2 hours after taking the drug, t1/2 is 5 to 7 hours, and a single dose of 1 to 3g is taken. The pharmacokinetics show a dose-linear relationship, the apparent volume of distribution is about 0.8L/kg, and the relative bioavailability is 92±11%.

France's Sanofi Vigabatrin is suitable for the treatment of intractable partial epilepsy, especially for intractable epilepsy in children.

France's Sanofi is the largest pharmaceutical company in Europe and the third largest in the world. It was established in 2004 through the merger of Sanofi-Synthelabo and Aventis. Headquartered in Paris, it has branches in more than 80 countries, more than 100,000 employees, and a turnover of more than 25 billion euros in 2004.

What are the side effects of French Sanofi's vigabatrin?

1. Vigabatrin may cause drowsiness, dizziness and visual field loss. You should avoid driving or operating machinery and other tasks that require vision and alertness.

2. Serious side effects: If symptoms such as visual field defects, blurred vision, drowsiness, hallucinations, emotional imbalance, depression, unconsciousness, or a sudden increase in the number of attacks occur, please seek medical attention immediately.

3. Other side effects: drowsiness, fatigue, headache, dizziness, weight gain, gastrointestinal discomfort, etc. Weight gain and mild gastrointestinal discomfort may be seen. Patients with myoclonic epilepsy may have an increased number of seizures. Children may become excited and anxious.

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