儿童应该怎样服用氨己烯酸片？长期用有哪些副作用

Vigabatrin is an analog of gamma-aminobutyric acid (GABA). It can specifically bind to GABA aminotransferase and irreversibly, leading to an increase in GABA concentration in the brain, thus exerting anti-epileptic effects. As adjuvant therapy, vigabatrin tablets can be used to treat patients who are refractory to other anti-epileptic drugs, especially those with partial seizures (mainly used to control complex partial seizures); it can also be used in infants with West syndrome (infantile spasms). As an auxiliary treatment drug, Vigabatrin tablets can achieve better efficacy. How should children take it? What are the side effects of long-term use?

How to use vigabatrin tablets

-General usage: For children aged 3-9 years, the recommended dose of vigabatrin is 1g per day, taken in 2 divided doses; for older children, 2g per day, taken in 2 divided doses.

West syndrome: Average oral dose is 100 mg/kg daily (range 50-150 mg/kg). Because each patient's disease progression and tolerance to drugs are different, the dosage and duration of treatment will also be different. The specific dosage of Vigabatrin tablets used by patients to treat epilepsy is mainly determined by the patient's condition, tolerance to drugs, and personal constitution, and cannot be generalized. Patients should strictly follow the doctor's diagnosis and treatment recommendations.

Vigabatrin tablets side effects

The side effects of Vigabatrin tablets include: fatigue, drowsiness, headache, dizziness, confusion, depression, memory loss, weight gain, gastrointestinal disorders, edema, alopecia, nystagmus, nervousness, irritability, ataxia, irreversible visual field defects, reduced hemoglobin and aminotransferase values, etc. If patients feel unwell during Vigabatrin treatment, they must go to the hospital and a professional doctor will diagnose whether the patient needs to continue taking the medication.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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