氯巴占是什么药？氯巴占的副作用是什么？

Clobazam is a long-acting benzodiazepine with similar pharmacological effects to diazepam. It has minimal sedative side effects and is more suitable for auxiliary treatment of epilepsy in adults. It is suitable for the treatment of refractory epilepsy that is ineffective against other anti-epileptic drugs. It is a mature and old drug that is widely approved for use internationally. However, currently, there are neither imported drugs nor generic drugs approved for marketing in China.

It is easy to absorb when taken orally, and reaches the peak value in blood within 1-4 hours, and is 85% bound to plasma proteins. Metabolized in the liver via demethylation and hydroxylation. Established in 2 multicenter controlled studies involving children ≥2 years of age. The study measured weekly reductions in the number of fall episodes from a 4-week baseline period to a maintenance period. In both studies, patients taking clobazam had improved seizure control and significantly improved anxiety and seizures compared with the control group. Clobazam can be used alone or as an auxiliary treatment. After clobazam (Frisium) enters the body, it is absorbed quickly and the effect is very good.

The recommended adult dose of clobazam for the treatment of refractory epilepsy refractory to other antiepileptic drugs is 5 mg to 80 mg daily, taken in 1 or 2 divided doses, with or without food, as directed by your doctor. However, the drug also has side effects. Blurred vision, constipation, decreased interest in sexual activities, dizziness, drowsiness, dry mouth, headache, loss of appetite, loss of muscle coordination, nausea, nervousness, fatigue, weight gain, etc. are the more common side effects of clobazam. It is recommended that patients follow the doctor's instructions and take medications according to the symptoms, and do not make blind choices.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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