卢非酰胺治疗癫痫的副作用及处理

Rufinamide is suitable for the adjuvant treatment of epileptic seizures related to Lennox-Gastaut syndrome (LGS) in pediatric patients 1 year old and above and adults. The main side effects include: central nervous system, digestive system, blood system, skin allergies, liver function damage, etc. The main manifestations are: headache, dizziness, mental abnormality, fatigue, nausea, vomiting, diarrhea, leukopenia, rash, itching, urticaria, etc. Usually patients have different physiques and conditions, and the side effects are also different.

Treatment of side effects of rufinamide in the treatment of epilepsy

Common side effects such as dizziness, headache, nausea, psychosis, memory loss and other uncomfortable reactions will gradually disappear after stopping the medication. If the patient develops intolerance during the medication, he/she needs to contact the doctor in time for symptomatic treatment.

Liver function tests should be carried out regularly during the medication. If drug allergic reactions or severe liver function damage occur, you should stop using this drug and seek medical treatment in time.

During rufinamide treatment, patients should try not to eat irritating foods, such as spicy foods and acidic foods, avoid excessive drinking, pay attention to diet and living habits, and have a regular schedule.

It is recommended that patients take medication under the guidance of a doctor, and do not adjust the dosage and usage at will, so as not to affect the treatment of the original condition.

The effects of rufinamide

Rufinamide is mainly used for the adjuvant treatment of Lennox-Gastaut syndrome (LGS). It mainly exerts anti-epileptic effects by regulating sodium channel activity. It is a new type of anti-epileptic drug. The initial dose of rufinamide is 400 mg/day, divided into 2 oral doses; if the dose needs to be gradually increased, each dose increase should take at least 2 weeks.

Rufinamide is a GABA analog that enhances the neurotransmitter effects of GABA, thereby exerting a calming effect. At the same time, it is also a central nervous system depressant, which can inhibit brain nerve signals and inhibit epileptic seizures. Pregnant women, lactating women, children and the elderly should use it with caution.

Before using rufinamide, you need to consult a doctor, and choose the dosage form and method of taking according to the doctor's advice; inform the doctor about the patient's previous medical history and all the drugs used before taking the medicine; pay attention to the body's reaction during the medication, and if there is intolerance, treat it under the guidance of the doctor in time without delay.

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