伐度司他(Vadadustat)正品的最新价格

Valadostat works by regulating erythropoietin (EPO) and iron metabolism. It was first approved in Japan in 2020 and approved by the US FDA in 2023. This article will focus on analyzing the latest price, medication precautions, and care points for patients with chronic kidney disease.

The latest price of genuine Vadadustat

The original drug of Vadadustat is produced by MEDICE, Germany. The specification is 300mg*98 tablets/box. The current market price is about US$320. Currently, there are no generic drugs on the market. Patients need to be wary of low-priced drugs from informal channels and avoid purchasing fake and inferior products.

Prices may fluctuate due to transportation, tariffs or regional policies. The above prices are for reference only. It is recommended to consult professionals in advance for the latest quotes.

Precautions for Vadadustat

Scientific use of medication can reduce treatment risks. The following are key precautions:

Contraindications for drug combination

Avoid taking iron-containing drugs such as polysaccharide iron complex at the same time, with an interval of at least 1 hour. When combined with simvastatin, the statin dose needs to be limited to 20 mg/day to prevent the risk of muscle damage. When using diuretics such as furosemide, it is necessary to monitor serum potassium levels to prevent electrolyte imbalance.

Liver function monitoring requirements

ALT, AST and bilirubin need to be tested before treatment, reviewed monthly in the initial stage of treatment, and monitored every 3 months after stabilization. If ALT/AST is >3 times the normal value or jaundice occurs, the drug must be stopped immediately and hepatoprotective treatment must be received. Patients with mild hepatic dysfunction require dose reduction and intensive follow-up.

Dose adjustment and suspension criteria

The standard adult dose is 300mg per day, and the tablet needs to be swallowed whole. If the hemoglobin (Hb) rise rate is >1g/dL/2 weeks or Hb is >11g/dL, the medication needs to be suspended until Hb falls back to the target range, and then the dosage is reduced to 150 mg/day. Those who are ineffective after 24 weeks of treatment need to stop taking the drug and re-evaluate the cause.

Daily care for patients with chronic kidney disease

Good daily care can delay disease progression and improve quality of life. The following are specific recommendations:

Diet and water management

Adopt a low-salt, low-phosphorus, high-quality protein diet, and control the daily protein intake at 0.6–0.8g/kg. Limit high-potassium foods such as bananas and potatoes to avoid raising blood potassium. Dialysis patients need to strictly record their daily water intake.

Prevention of complications

Regularly monitor blood pressure (target <140/90mmHg) and blood sugar to prevent cardiovascular events, keep skin clean, avoid scratching itchy areas, and reduce the risk of infection. Anemia patients can appropriately supplement vitamin B12 and folic acid, but they need to be under the guidance of a doctor.

Chronic kidney disease can easily cause anxiety or depression. Family members should encourage patients to participate in social activities and seek psychological counseling if necessary. Perform light exercise such as walking and Tai Chi for 20-30 minutes every day to improve blood circulation, but avoid excessive fatigue.