托伐普坦片主要治什么病,治疗多囊肾每天吃多少？

Polycystic kidney disease (PCK) rats are a human autosomal recessive polycystic kidney disease (ARPKD) model. In male and female polycystic kidney disease rats, dietary administration of tolvaptan tablets at concentrations of 0.01, 0.03 and 0.1% can inhibit the development of polycystic kidney disease (PKD), which is manifested by reduced kidney and cyst weight and reduced fibrosis volume. Renal cAMP concentrations were also reduced, and a positive correlation was found between tissue cAMP levels and PKD severity.

What diseases does Tolvaptan tablets mainly treat?

Tolvaptan tablets are indicated for the treatment of clinically apparent hypervolemic and normovolemic hyponatremia (serum sodium concentration <125 mEq/L, or hyponatremia that is not obvious but symptomatic and fluid restriction therapy is ineffective), including patients with heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone secretion (SIADH). At the same time, the drug also has a certain effect on polycystic kidney disease.

How much tolvaptan tablets should be taken daily to treat polycystic kidney disease?

The usual starting dose of tolvaptan tablets is 15 mg, once a day, before or after meals. After taking the medicine for at least 24 hours, the dosage can be increased to 30 mg once a day. Depending on the serum sodium concentration, the maximum dose can be increased to 60 mg, once daily. Changes in serum electrolytes and blood volume should be monitored frequently during initial administration and dose increase, and fluid restriction should be avoided during the first 24 hours of treatment. Patients taking this product should drink water when thirsty

Here, the editor of Medical Companion Travel would like to remind everyone that if you choose to use tolvaptan tablets, you must follow the doctor's instructions and take the medication strictly in accordance with the doctor's instructions. At present, due to the development of the Internet, there is a lot of unfounded information, which makes many patients think that the efficacy can be improved by increasing the dose of drugs, or that side effects can be avoided by reducing the dose of drugs. These are wrong, and patients are expected to use drugs rationally.

Note: The above information comes from the Internet and is compiled and edited by Medical Companion Travel (please correct me if there are any errors or omissions). It is only to provide information on the latest drugs on the market in the world and help Chinese patients understand the latest international new drug trends. It is only for internal discussion among medical staff and does not serve as any basis for medication. For specific medication guidelines, please consult the attending physician.

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