sirolimus如何购买呢？

Sirolimus is a lipophilic macrolide antibiotic extracted from hygroscopic bacteria of the genus Streptomyces. It targets mammals and is a mammalian targets of rapamycin inhibitors (mTOR-I) inhibitor. It mainly plays a role by forming a complex with FKBPl2 (a protein family with peptidyl-prolyl cis-trans isomerase activity, cyclophilins) and then binding to mTORl to regulate the levels of certain factors to regulate protein synthesis, angiogenesis, lipid biosynthesis, mitochondrial biological functions, cell cycle, autophagy, etc. Kidney transplant patients can also benefit a lot from taking this drug.

So, how to buy such effective sirolimus?

As early as 2000, sirolimus had been approved for domestic marketing. From that time on, patients could purchase the drugs they needed at major domestic hospitals and pharmacies without going abroad. According to the official display of the China Medical Information Query Platform, the reference price of this drug is 143.00$~2739.00$. Normally, patients can buy a box of the small-sized medicines they need for about $500.

At present, Leipamin has been included in the medical insurance catalog and belongs to the Class B drug of medical insurance. This also means that when patients purchase the drug in China, they can rely on medical insurance to reimburse part of the cost, thereby reducing their out-of-pocket expenses and reducing their own financial burden. Normally, the medical insurance reimbursement ratio is around 70% to 80%. However, it is affected by the medical insurance policies of various regions and other factors, so there will be certain differences in the final reimbursement ratio. Specific patients can consult the relevant departments.

Due to the different dosage forms and specifications of sirolimus, its usage and dosage may vary. Therefore, patients must carefully read the specific drug instructions or follow the doctor's advice before receiving treatment with this drug.