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(Sirolimus) is a triangular white or off-white sugar-coated tablet. Rapamin (Sirolimus) is suitable for patients receiving kidney transplants to prevent organ rejection. It is recommended to be used in combination with cyclosporine and corticosteroids. Rapamin (sirolimus) is recommended for combined use with cyclosporine and corticosteroids. Take orally, once daily. It should be started as soon as possible after transplantation. For new transplant recipients, the loading dose of rapamin (sirolimus) should be three times the maintenance dose.

Rapamin (sirolimus) is suitable for patients receiving kidney transplants to prevent organ rejection. Clinical recommendations include the combined use of rapamycin (sirolimus) with cyclosporine and corticosteroids. This medicine should be started as soon as possible after transplantation. For new transplant recipients, the loading dose of this drug should be taken for the first time, that is, 3 times the maintenance dose. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day. Although the loading dose of 15 mg and the maintenance dose of 5 mg/day used in clinical trials are safe and effective, the therapeutic benefits of doses above 2 mg are unclear for kidney transplant patients.

First of all, after kidney transplant surgery, it is generally required to have weekly follow-up visits within two to three months. First, the concentration of anti-rejection drugs must be observed, because the bioavailability of anti-rejection drugs has very large individual differences. It must be maintained at an ideal level, and it is not good for the patient if the concentration is high or low. If the concentration is too high, poisoning may occur and creatinine will increase. Rejection may occur if the concentration is too low. Therefore, post-operative care requires regular follow-up visits.

In addition, for patients after discharge, they must also be taught overall care in terms of clothing, food, housing, and transportation, such as learning to keep warm and not to catch cold easily. Because patients are in a state of immunosuppression, they are prone to infection if they catch a slight cold. Avoid going to crowded places, especially people with infectious diseases or colds, and try to avoid contact with them. Because the purpose of anti-rejection drugs is to lower the immune system, it is not recommended to eat drugs or foods that can significantly improve immunity. Avoid taking ginseng, royal jelly, fungus and other tonics. Moderate exercise is required in the early postoperative period, but it should not be too intense. Generally speaking, when every kidney transplant patient is discharged from the hospital, medical staff will give comprehensive advice on all aspects.

Patients must read the instructions carefully before taking (sirolimus) and pay attention to medication safety.