雷帕鸣适应于哪些人群吃

(sirolimus) is a targeted inhibitor of the target of rapamycin (roTOR). It is a powerful immunosuppressant with low nephrotoxicity, anti-proliferation, and anti-tumor effects, and is suitable for kidney transplant patients.

Patients who have undergone kidney transplantation can use the drug Rapamin under the guidance of a doctor. Friends who need it can go to major local hospitals and pharmacies to buy this drug. At the same time, it is also recommended that patients understand the precautions after organ transplantation, which will help control the condition.

Under normal circumstances, patients who have undergone organ transplantation need to pay special attention to their diet. They must eat less salt, sugar and oil, and have a lighter diet. You can eat more fruits, vegetables and whole grains, which are easier to digest and will not burden the body. In addition, they must be careful not to eat high-tonifying foods, and do not eat too much food because of It will be counterproductive to heavily supplement the body after surgery. For patients who have undergone organ transplants, if they take supplements, the body will be unbearable. In addition, they should go to the hospital regularly for relevant examinations to see if there are other complications. At the same time, they can further observe their physical recovery.

The recommended usage of rapamin (sirolimus tablets) is orally administered once daily. After transplantation, patients should start taking it as soon as possible. For de novo kidney transplant recipients, sirolimus is recommended in combination with cyclosporine and corticosteroids. A loading dose of sirolimus should be taken for the first time, which is 3 times the maintenance dose. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day. To maintain sirolimus plasma concentrations within the target range, sirolimus plasma concentrations should be monitored. Although the loading dose of 15 mg and the maintenance dose of 5 mg/day used in clinical trials are safe and effective, the efficacy benefits of doses above 2 mg are unclear for kidney transplant patients. The overall safety profile of patients taking 2 mg of sirolimus oral solution daily was better than that of patients taking 5 mg sirolimus oral solution daily.

Recommended hot articles: /newsDetail/72900.html