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For patients undergoing kidney transplantation, it is recommended to be used in combination with cyclosporine and corticosteroids to prevent organ rejection.

Rapamin sirolimus tablets are the metabolites of nitrogen-containing macrolide microorganisms. They have special structural groups, that is, the lactone ring contains 1 molecule of non-protein amino acid - pipecolic acid. Through the pipecoyl group, it interacts with FKBPs, a type of intracellular immunoaffinity protein with prolyl cis-trans isomerase activity to form a complex. It acts on different target sites in cells and exerts a variety of different biological functions.

The mechanism of action of Rapamin and Sirolimus Tablets is: Rapamin and Sirolimus Tablets inhibit the activation and proliferation of T lymphocytes stimulated by antigens and cytokines. It also inhibits the production of antibodies. In cells, rapamycin sirolimus binds to the immunophilin, FK-binding protein-12 (FKBP-12), to generate the FKBP-12 immunosuppressive complex. This complex binds to the mammalian sirolimus BA molecule and inhibits its activity, thereby inhibiting the progression from G1 to S phase in the cell cycle.

The therapeutic effect of rapamin sirolimus tablets is remarkable, and the successful development of this drug is good news for many patients. Taking rapamin sirolimus tablets for treatment will also produce certain side effects or adverse reactions, including: peripheral edema/hypertension/edema/chest pain/deep vein thrombosis/pulmonary embolism/headache/pain/dizziness/acne vulgaris/hypertriglyceridemia/diabetes/ovarian cyst/constipation/diarrhea/stomatitis, etc.

Where can I buy Repana sirolimus tablets?

It is understood that it has been launched in China, and patients can purchase the drug at major domestic pharmacies with a prescription issued by a doctor. Rapamin Sirolimus tablets produced by Biocon Pharmaceuticals in India are 1 mg x 10 tablets and sell for about $200. Due to factors such as exchange rate fluctuations, the price is not fixed. If patients want to know the specific price information of rapamin sirolimus tablets, or want to purchase the drug overseas, they can consult with domestic reliable overseas medical service institutions (such as Medical Companion Travel).

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