雷帕鸣价格贵吗

The price of medicines will also affect patients’ choices. So is the price of Biocon produced in India expensive?

It is reported that Leipaming was launched in China at the end of 2003. In terms of price, Rapamin produced by Biocon in India is about $200. Patients can consult Medical Companion Travel Service to learn about the specific drug purchase process. If you have relevant questions, you can also ask Medical Companion Travel Service.

Rapamin inhibits the activation and proliferation of T lymphocytes stimulated by antigens and cytokines (interleukins IL-2, IL-4 and IL-15). It also inhibits the production of antibodies. In cells, rapamycin binds to the immunophilin, FK-binding protein-12 (FKBP-12), to generate the FKBP-12 immunosuppressive complex. This complex binds to the mammalian rapamycin BA molecule (mTOR, a key regulatory kinase) and inhibits its activity, thereby inhibiting the progression from the G1 phase to the S phase in the cell cycle.

Concomitant use of rapamycin with cyclosporine and corticosteroids is recommended. Take orally, once daily. It should be started as soon as possible after transplantation. For new transplant recipients, the loading dose should be taken, which is 3 times the maintenance dose. The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day. Although the loading dose of 15 mg and the maintenance dose of 5 mg/day used in clinical trials are satisfactory, the therapeutic benefit of doses above 2 mg is unclear for kidney transplant patients.

Rapamin is rapidly absorbed after oral solution, with an average time to peak of approximately 1 hour after a single oral dose; in renal transplant recipients, the average time to peak after multiple oral doses is approximately 2 hours. High-fat meals can increase the absorption of rapamin, so it is recommended that oral rapamin should be taken regularly with or without food.

Patients who receive a kidney transplant must have a perseverant attitude and actively cooperate with the doctor's treatment. Warm reminder: It is recommended that patients who have been diagnosed can use it under the guidance of a doctor, but they are not allowed to change the dosage of the drug without authorization to avoid adverse drug reactions.

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