雷帕鸣使用说明

It is a new, powerful, low-toxic macrolide immunosuppressive drug. It is mainly used clinically to prevent rejection of kidney transplants. It does not inhibit calcineurin after binding to cytoplasmic proteins, so it can completely avoid the nephrotoxicity of calcineurin inhibitors (CNI). It is one of the best choices when liver or kidney insufficiency occurs after organ transplantation or when CNI cannot reach the ideal drug concentration.

For patients who receive a kidney transplant, rejection after surgery is what everyone is most worried about. This may mean that the surgical treatment fails and the patient cannot survive long-term. The launch of Rapamin brings new hope for the treatment of patients.

Rapamin was approved for marketing in China in 2002. In addition to the domestic original drug, India has also launched the generic version of Rapamin produced by Biocon. Biocon is one of the three major biotechnology companies in India. Its goal is to achieve health equity. Rapamin is favored by patients because of its relatively low price. The drug can be used in the same way as the original drug.

Rapamide is available in tablets, capsules, oral solutions and other dosage forms. As a prescription drug, Rapamin is only for use by physicians experienced in immunosuppressive therapy and handling kidney transplant patients. It is recommended to use it in combination with cyclosporine and corticosteroids. Patients should not take medication blindly. Tablet usage is as follows: The recommended loading dose for kidney transplant patients is 6 mg and the maintenance dose is 2 mg/day. It should be started as soon as possible after transplantation.

Rapamide can be taken with or without food. Tablets should be swallowed whole and should not be chewed or crushed. If the patient has difficulty swallowing, an oral solution should be chosen. If dosage adjustment is necessary, this should be done on the advice of a physician. Overdosing can cause some additional side effects.

It is prohibited to use if the patient is allergic to its ingredients. Effective contraception should be used before starting treatment with rapamin, during treatment and for 12 weeks after stopping treatment. Use by pregnant women requires an assessment of the risks and benefits.

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