西罗莫司在中国上市了吗？

Inhibits the activation and proliferation of T lymphocytes stimulated by antigens and cytokines (interleukins IL-2, IL-4 and IL-15). It also inhibits the production of antibodies. Rapamin is a macrolide antibiotic that can be used long-term to help improve disease. So, has India Biocon’s sirolimus been launched in China?

Sirolimus tablets were approved in 2002 and officially launched in China, bringing new treatment opportunities and options to many domestic kidney transplant patients. Previously, the drug had been approved by the FDA in 1999 and was officially launched in the United States.

The original drug sirolimus is produced by Pfizer. Although the original drug has been on the market in China for many years, the price of the original drug is usually relatively high, while the sirolimus produced by India's Biocon is relatively cheap.

Biocon is one of India's three largest biotech companies and an emerging global biopharmaceutical company that is committed to reducing the cost of treatment for chronic diseases such as diabetes, cancer and autoimmune disease patients by leveraging India's cost advantages and partners to provide affordable healthcare solutions to healthcare systems around the world.

Sirolimus tablets are a macrolide antibiotic isolated from actinomycete cultures. It was originally developed as an antifungal drug, but it showed immunosuppressive effects in animal models and was later approved as a maintenance immunosuppressant. Sirolimus has attracted clinical attention and is widely used because of its advantages such as non-nephrotoxicity, anti-tumor, and ability to reduce the incidence of cytomegalovirus infection.

Sirolimus needs to be started as soon as possible after transplantation. The recommended loading dose of rapamycin for renal transplant patients is 6 mg and the maintenance dose is 2 mg/day. Tablets need to be swallowed whole and not chewed or broken. If the patient has difficulty swallowing, an oral solution should be chosen. It can be taken with or without food. If the dosage needs to be adjusted, it should be done under the advice of a doctor.