The therapeutic effect and clinical data of tenofovir alafenamide fumarate tablets (Vemlidy)

Tenofovir alafenamide fumarate tablets (Vemlidy/Vemlidy), as a new generation of tenofovir prodrug, is a highly discussed oral drug in the field of chronic hepatitis B antiviral treatment in recent years. Its core advantages are"high efficiency, low toxicity, and long-term controllability", especially in hepatitis B patients who require long-term treatment. Compared with traditional tenofovir preparations, Vemlidy can release active ingredients in the liver at a lower dose, making it more advantageous in protecting kidney function and bone density. This is one of the important reasons why many guidelines recommend it as the drug of choice.

In terms of therapeutic effect,Vemlidy can continuously inhibit the replication of hepatitis B virus in the blood, reduce the amount of virus to an undetectable level, and improve liver inflammatory activity. Multicenter studies have shown that patients using Vemlidy often achieve sustained virological suppression during long-term treatment, and liver function indicators show a gradual improvement trend. Its stable antiviral efficacy makes it a powerful choice for maintenance treatment and long-term disease management for patients with chronic hepatitis B.

A major feature of Vemlidy is its higher liver targeting. As a highly optimized prodrug form, it can more effectively deliver the active ingredient in the body and avoid the risks to bones and kidneys caused by traditional tenofovir at high doses. Therefore, Vemlidy is often considered a safer long-term treatment option for patients with borderline renal function or at risk for osteopenia.

Vemlidy is also well tolerated under long-term use.Vemlidy is also well tolerated. Most patients will not experience any obvious discomfort during treatment and can usually continue taking it without frequent dosage adjustments. Real-world data also shows that this class of drugs exhibits good stability in long-term observation, and patients have durable and reliable performance in virus control.

Reference materials:https://www.vemlidyhcp.com/