Where can I buy Seladelpar in the country?

Seladelpar (Seladelpar) is a new type of selective PPARδ receptor agonist, mainly used to treat primary biliary cholangitis (PBC) disease. Due to its unique role in regulating bile acid metabolism and inflammatory response, it has attracted attention in overseas clinical research in recent years. However, Siladepa has not yet been officially launched in China, so patients cannot directly purchase the drug in regular domestic pharmacies or hospital pharmacies. This current situation means that if domestic patients need to use Siladepa for treatment, they can only obtain it by participating in clinical trials or through international medical channels, and must use it under the guidance of a doctor.

In overseas markets,Seladelpar’s original drug is usually sold under the brand name Livdelzi, with a specification of 10mg*30 pills per box. Due to the cost of research and development, patent protection and cross-border circulation, the price of original drugs is relatively high, and each box may be sold for more than 10,000 US dollars. The price may be adjusted at any time due to fluctuations in exchange rates and international logistics. In order to reduce the burden on patients, some countries and regions provide generic drugs with the same specifications and basically the same ingredients, but the price is only about one-third of the original drug, for example, about 3,600 yuan per box. Generic drugs are usually equivalent in efficacy to the original drugs, but they need to be from regular sources to avoid drug quality and safety risks.

It is worth noting that if domestic patients purchase overseas drugs through informal channels, there are legal and health risks, including difficulty in ensuring the authenticity of the drugs, substandard transportation conditions, and lack of necessary medication monitoring. Therefore, doctors usually recommend that patients wait for the drug to be launched domestically or participate in eligible international clinical trials to ensure treatment safety and efficacy monitoring. Overseas guidelines also emphasize that the use of Seladelpar must be based on the patient's specific condition, liver function status and other basic diseases, and the dosage and treatment course must be reasonably arranged.

Reference materials:https://go.drugbank.com/drugs/DB12390