How much does a box of sofosbuvir and velpatasvir (Epclusa) cost?

The combination of sofosbuvir and velpatasvir (Epclusa) is used alone or with ribavirin (Copegus) to treat chronic hepatitis C (a persistent viral infection that damages the liver) in adults and children 6 years and older or who weigh at least 37 pounds (17 kilograms).

Sofosbuvir belongs to a class of antiviral drugs called nucleotide hepatitis C virus (HCV) NS5B polymerase inhibitors. Velpatasvir is an antiviral drug called HCV NS5A replication complex inhibitor. The combination of sofosbuvir and velpatasvir works by stopping the spread of the virus that causes hepatitis C in the body. The combination of sofosbuvir and velpatasvir is an oral tablet that is usually taken once daily with or without food for 12 weeks. Even if you feel well, continue taking sofosbuvir and velpatasvir combination. Do not stop taking sofosbuvir and velpatasvir combination without consulting your doctor.

The original drug of sofosbuvir and velpatasvir has been launched in China and has entered the scope of Class B medical insurance. The domestic trade name is Bintongsha, and the specification is (400mg+100mg) * 28 tablets. The price per box is around RMB 4,000. The reimbursement ratio is different in different regions, and the price after reimbursement may be different. The original drug of sofosbuvir and velpatasvir has also been launched overseas. There are also generic drugs of sofosbuvir and velpatasvir produced in other countries. The specifications of the Bangladesh Everest Pharmaceutical Factory are (400mg + 100mg) * 28 tablets per box, and the price is around RMB 850 (the price may fluctuate due to the exchange rate). The generic drugs produced abroad are basically the same as the original drugs at home and abroad.